Constipation

2019

Constipation - Controlled randomized trial

Magnesium-rich formula for functional constipation in infants: a randomized comparator-controlled study

Pediatric Gastroenteroly, Hepatology & Nutrition, 2019 May, 22(3):270-281

Benninga MA, Mena Infant Constipation Study Group, Vandenplas Y

Abstract

The aim is to compare the effectiveness of the magnesium (Mg)-enriched formula vs. control formula in constipated infants.

2011

Biochemical evidence

Modification of stool's water content in constipated infants: management with an adapted infant formula

Nutrition Journal, 2011, 10:55

Infante DD, Segarra OO, Redecillas SS, Alvarez MM, Miserachs MM

Abstract

Constipation is a common occurrence in formula-fed infants. The aim of this preliminary study was to evaluate the impact of a formula with high levels of lactose and magnesium, in compliance with the official regulations, on stool water content, as well as a parental assessment of constipation.

2008

Prevalence of GI disorders - Efficacy in management

Prevalence and dietetic management of mild gastrointestinal disorders in milk-fed infants

World Journal of Gastroenterology, 2008, 14(2):248-54

Infante Pina D, Badia Llach X, Ariño-Armengol B, Villegas Iglesias V

Abstract

The aim is to assess the prevalence of mild gastrointestinal disorders in milk-fed infants in paediatric practice, and to evaluate the effectiveness and satisfaction with dietetic treatment.

2007

Efficacy

Therapeutic effect of Novalac-IT in infants with constipation

Nutrition, 2007, 23(6):469-73

Chao HC, Vandenplas Y

Abstract

Infant constipation is a frequent condition in formula-fed infants.

A prospective randomized clinical trial was performed in infants who had constipation with Novalac-IT (IT group) versus a 20% strengthened formula (S group). Enrolled subjects had difficulties in defecating, hard stools, or low frequency of defecation (< or =3 times/wk) (...).

2002

Hirschsprung's disease, prevention of constipation

Preventive use of a milk causing intestinal hyperosmolarity, from infants having operated for Hirschsprung's disease

Revue Internationale de Pédiatrie, 2002, Tome XXXIII, n° 319:28-30

Smarropoulos E, Liolios N, Netskos D, Anagnostopoulos D

Abstract

Constipation may be early or a late complication of the surgical management, according to the Duhamel procedure, in infants affected by Hirschsprung's disease. The present study aims to assess the response of infant's gastrointestinal system towards the follow-on formula Novalac IT2. The aspect and frequency of the stools as well as the characteristics of defecation are observed in two groups of 5 infants each fed either Novalac IT2 or standard follow-on formula.

The results are impressive from the first 24 hours with the observation of soft stools in every infant fed with Novalac IT2. Novlaac IT2 promotes intestinal intraluminal osmolarity leading to normal defecations associated with minimal discomfort, as well as parents' reassurance who saw for the first time their child relieved.

Furthermore, none of the subjects fed with Novalac IT2 ever visited again the hospital because of constipation, meaning economy for both, families and medical personnel.